'Dhol - Kiska Bajega' revolves around the lives of four friends - Sam (Tusshar Kapoor), Pakkya (Sharman Joshi), Maru (Rajpal Yadav) and Goti (Kunal Khemu). The guys are good for nothing with no motivation. But they're bound together by their child-like notoriety and aimlessness. They all want to make it big in life with the least efforts possible. The four wish to live life on their own terms, leading everyone to nowhere. As a result, each one tries their hand at finding a short cut to success but ends up being in even deeper trouble instead. Things get worse as the four decide to take some desperate measures to end their misery once and for all.