Shirin Farhad Ki Toh Nikal Padi is an unusual romantic-comedy, that revolves around 45-year-old Farhad Pastakiya (Boman Irani), a golden-hearted Parsi bachelor, who has never had any girlfriend in his life. Farhad, who is a loungerie salesman, has only one woman in his life and she is none other than his dominating mother Nargis. One fine day he meets 40-year-old Shirin Fugawala (Farah), and falls in love at first sight. But all hell breaks loose as Farhad`s mother Nargis realises that her son's dream girl (Shirin) is her sworn enemy. Next what happens? Will Farhad become successful in convincing his mother and marry Shirin? Or, he has to sacrifice his ladylove for life?