Annu Kapoor made his debut in the film Kaala Patthar in 1979 His career has spanned nearly 34 years including a distinctive presence in Bollywood cinema, television serials, and reality game shows. He is best remembered for hosting the singing show Antakshari produced by silver screen veteran Gajendra Singh. He recently won critical acclaim for his character of a neighbor and debt collector in Raincoat (film) in 2004.
In 2007 the mega hit programme Antakshari came back from the dead on Star One. It was widely publicized in 2006 that it was going to end for ever and a grand grand finale was held for the same. During its initial course of running, Antakshari ran from 1993 to 2006 on Zee TV.
Annu Kapoor is now hosting Antakshari: The Great Challenge, Juhi Parmar, on Star Plus.
Annu Kapoor is a follower of numerology. With the coming of Antakshari-The Great Challenge on Star One, he has changed the spelling of his last name from Kapoor to Kapur (along with Gajendra Singh who spells his name with an extra 'R' in the first name, and an extra 'I' in the last name.)
In the October 3, 2007 episode of the DD National show Music, Masti aur Dhoom, Anu Kapoor stated that he wanted to become a surgeon, but he could not afford to study as his family was poor. In an episode of the DD National show Wheel Smart Shrimati, he mentioned that he was born in Indore.