Brand made a series of political, sexual and off-colour remarks throughout the night, reportedly annoying some of the celebrities in attendance. However, his wildest remark was aimed at Alaska governor Palin. "The safe sex message is to use a condom or become a Republican," Fox quoted Brand, as saying.
The comedian angered some in attendance by repeatedly joking about the Jonas Brothers, who wear purity rings as a symbol of their vow not to have premarital sex. The Forgetting Sarah Marshall funnyman also encouraged Americans to vote for Democratic presidential candidate Barack Obama in the upcoming election, referred to George W. Bush as a 'retarded cowboy fella'.