Boss, a mix of humour and action, revolves around gang wars between two Kochi-based notorious groups, led by Boss (Suresh Gopi) and Mallikkettu (Kalabhavan Mani). The Boss' gang includes veterans Innocent, T.G. Ravi, Cochin Haneefa, Harisree Asokan, Undapakru and Santosh Jogi while Mallikkettu's gang is packed with hulky thugs. Boss is a big time international gangster who operates from Kochi, Goa and Dubai. With the arrival of Pooja (Vasundhara Das), a top Tamil-Telugu actor, the situation changes quite abruptly, bringing a suspense twist in the story.
Satheesh K. Sivan and Suresh Menon have penned the script. Salu George wields the camera. Boss will be released during Ramzan. The other locations of the film include Alappuzha and Goa.