Chandramukhi 2 is a remake of Kannada blockbuster movie Aptharakshaka, which starred late Sandalwood matinee idol Dr Vishnuvardhan in the lead. The movie is reportedly produced by Sivaji Productions, and the production house bosses have approached Ajith Kumar again and convinced him. They had earlier met him and offered the same but later the plans were temporarily shelved, as the Telugu version titled Nagavalli starring Venkatesh got moderate response.
Later, Ajith Kumar went on to do Mankatha followed by Billa 2. He is currently busy with Vishnuvardhan's directorial untitled movie and his next is expected to be a commercial movie directed by T Siva of Siruthai fame. The project could only start after the completion of these movies. However, the first instalment starred Rajinikanth, Jyothika and Nayantara in the leads.