Kumkuma is family based movie in which, Madhuri (Seema) is a gynecologist who marries a fashion designer Karthik (Siva Balaji). Karthik dies in an accident. She joins the clinic run by Vamsi (Jayant). Vamsi proposes to marry her. Madhuri is reluctant but she is pursued by her father-in-law (Ranganath) to marry Vamsi. After their marriage, Vamsi introduces his patient called Balaji who is suffering from amnesia. Balaji looks exactly like Karthik and Madhuri doubts that Balaji could be Karthik. The rest of the story is all about the emotional struggle Madhuri.