Mujhse Shaadi Karogi starts with the character Sameer who is a hot-headed youngsters with a knack of getting into brawls. When his girlfriend dumps him, he is heartbroken and relocates to Goa to work as a lifeguard.
He falls for his next-door neighbour Rani, but Rani dislikes him because Sameer had slapped her father by mistake. On top of it, Sameer's new roommate Sunny is a lecherous playboy who has the hots for Rani. This results into a zany battle of wits between Sameer and Sunny over who will win Rani's heart