In Meri Aashiqui Tum Se Hi, Ishaani (Radhika Madan) is on a mission to impress Ranveer aka RV (Shakti Arora) and win his love, while Amba is trying to separate them. For this, Amba is now trying the first option that the lawyer had suggested her - Prove Ishaani mad. Other two options that he gave were: Prove Ishaani has extra marital affair and RV doesn't want any relation with his wife.
Amba and Lakshmi are seen organising a party for orphans. Lakshmi pretends over phone that the joker, who promised to entertain children, will not be able to come. Listening to this, Ishaani agrees to become joker, while her brother resists, but she says that she can do anything to save RV's reputation.
On the other hand, Ishaani's sister Disha will be caught going to maternity hospital by Baa. Disha, who was to go to parlour as her marriage was all set for next day, would be congratulated by doctor. When Baa asks her the reason why she is in that hospital, Disha escapes saying that she had come to see her friend who delivered baby girl.
The other track of the serial shows Ritika appreciating Sharman for his wonderful presentation at office and says they will definitely get the project. While on the way, they find injured dog, and worried Ritika takes the dog in the car. Sharman, seeing this, says that she is worried about dog and not traffic jam! She says the dog was in pain and they have to get rid of traffic soon. Ritika asks the help of traffic police, who agrees.
While in the party, Ishaani enters the stage dancing, but suddenly the music goes off. All are stunned to see Ishaani as joker. RV, who is with his corporate guests, looks angry and asks them to ignore. Amba calls doctor and says Ishaani is mad. Seeing this all are stunned. She further says that Ishaani had even burnt the bed, and behaves like this always. Now she is even more scared that with this attitude, Ishaani can harm anyone.
Ishaani tries to explain that she thought it was children's party. Her brothers even support her with this. When Ishaani calls RV for help, Amba says that he had already left the party. Doctor asks his staff to examine Ishaani to certify her mentally unstable.
Derwash calls Sharman and asks for his help as Ishaani is in trouble. While doctors were taking her in the ambulance, Sharman and Ritika stop and say Ishaani isn't mad. Meanwhile, the dog jumps out of the car and bites Amba. They leave Ishaani and asks Amba for first aid, and check whether the dog has rabies. Ritika says the dog is just injured and isn't mad. Ishaani tries to console Amba, but RV interrupts and says he can take care of his family.
The doctors declare that Ishaani isn't mad, but Ishaani is seen accepting that she is mentally unstable and her mother-in-law Amba isn't wrong. Now it should be seen if the dog bite really changes Amba for good!