Rajkiran is a successful South Indian actor, primarily in Tamil language films. Some successful films with him in the lead role are Thavamai Thavamirundhu and Muni. He acted more than 150 films altogether.
Rajkiran began by producing two Ramarajan starrer films and in one of them he appeared in a brief role. In 1991, he produced and acted in lead role in Kasthuri Raja's drama film, En Rasavin Manasile which had a silver jubilee run.
He won the Tamil Nadu State Film Award Special Prize and the Cinema Express – Best New Face Award for his performance. He directed, produced and acted in lead role in Aranmanai Kili (1993) and Ellame En Rasathan (1995), which also had silver jubilee runs. In 1996, he acted in Manikkam which was an average grosser at the box-office. The following year,he worked in Pasamulla Pandiyare.
The film turned out to be a failure. In the mid of 1998, he acted in Ponnu Velayira Bhoomi and made a guest appearance in Kasthuri Raja's Veera Thalattu. In the end of 1998, he acted in the critically well received Thalaimurai. Following a three-year hiatus, he returned as an actor in Bala's Nandha and in Cheran's Pandavar Bhoomi.
Both were critical and commercial successes. He has won the Filmfare Best Tamil Supporting Actor Award for his performance in the film Thavamai Thavamirundhu (2005) and the Tamil Nadu government's Best Actor award for Pandavar Bhoomi (2001).