Lokesh was a Kannada film actor, who had acted in well-known Kannada films such as Bhootayyana Maga Ayyu, Kaadu and Kaakanakote. His wife Girija Lokesh is a film actress and film director. Lokesh died in 2004 after a prolonged illness. He is the son of Late Subbaiah Naidu, who is credited to be the first hero of Kananda silent movies. His son Srujan Lokesh is a well known Kannada actor and daughter Pooja Lokesh is a well known TV actress.